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            "id": "CG-PCER-VARINT:CA220146/MONDO:0018997/004/1/1838",
            "statementOutcome": {
              "@id": "SEPIO:0000224",
              "label": "Met"
            },
            "type": "CriterionAssessment"
          }
        ],
        "evidenceStrength": {
          "@id": "https://obofoundry.org/sepio"
        },
        "id": "CG-PCER-VARINT:CA220146/MONDO:0018997/004/0/1837",
        "type": "EvidenceLine"
      },
      {
        "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA220146/MONDO:0018997/004/el/0/1747",
        "evidenceItem": [
          {
            "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA220146/MONDO:0018997/004/ei/1/1748",
            "contribution": [
              {
                "agent": {
                  "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50021_EP155190663717081",
                  "id": "CG-PCER-AGENT:CG_50021_EP155190663717081",
                  "type": "Agent"
                },
                "contributionDate": {
                  "date": "2024/10/1",
                  "description": "Date on which this evidence was provided"
                },
                "contributionRole": {
                  "@id": "https://obofoundry.org/sepio/0000156",
                  "id": "SEPIO:0000516",
                  "label": "curator role",
                  "type": "ContributoryRole"
                },
                "type": "Contribution"
              }
            ],
            "evidenceLine": [
              {
                "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA220146/MONDO:0018997/004/el/0/1747/1749",
                "evidenceItem": [
                  {
                    "@id": "CG-PCER:curatorInference/CA220146/MONDO:0018997/004/ci/CA220146/MONDO:0018997/004.002",
                    "contribution": [
                      {
                        "agent": {
                          "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50021_EP155190663717081",
                          "id": "CG-PCER-AGENT:CG_50021_EP155190663717081",
                          "type": "Agent"
                        },
                        "comments": "Computational prediction tools and conservation analysis suggest that the p.Tyr63Cys variant may impact the protein (PP3).",
                        "contributionDate": {
                          "date": "2024/10/1",
                          "description": "Date on which this evidence was provided"
                        },
                        "contributionRole": {
                          "@id": "https://obofoundry.org/sepio/0000156",
                          "id": "SEPIO:0000516",
                          "label": "curator role",
                          "type": "ContributoryRole"
                        },
                        "type": "Contribution"
                      }
                    ],
                    "id": "CA220146/MONDO:0018997/004/ci/CA220146/MONDO:0018997/004.002",
                    "type": "InfFromBkgrndSciKnow"
                  }
                ],
                "id": "CG-PCER-VARINT:CA220146/MONDO:0018997/004/0/1747/1749",
                "type": "EvidenceLine"
              }
            ],
            "id": "CG-PCER-VARINT:CA220146/MONDO:0018997/004/1/1748",
            "statementOutcome": {
              "@id": "SEPIO:0000224",
              "label": "Met"
            },
            "type": "CriterionAssessment"
          }
        ],
        "evidenceStrength": {
          "@id": "https://obofoundry.org/sepio"
        },
        "id": "CG-PCER-VARINT:CA220146/MONDO:0018997/004/0/1747",
        "type": "EvidenceLine"
      }
    ],
    "id": "CG-PCER-VARINT:CA220146/MONDO:0018997/004",
    "metadata": {
      "created": "2024-10-01T21:10:45.581Z",
      "note": "DISCLAIMER: While the data/content in this document is approved by ClinGen expert panel(s), the SEPIO schema presented here is an initial prototype and has not been reviewed nor finalized by the ClinGen Data Exchange Modeling Team. We expect it to differ significantly from the final schema.",
      "producedAtUTC": "Tue, 01 Oct 2024 21:10:45 -0000",
      "schemaLabel": "Evidence Repository.Beta-1 (Unofficial)",
      "version": "1.1.0"
    },
    "statementOutcome": {
      "@id": "https://loinc.org/LA6668-3",
      "id": "LN:LA6668-3",
      "label": "Pathogenic"
    },
    "type": "VariantPathogenicityInterpretation",
    "uuid": "579af108-04e2-4cf7-9a40-35cbaa82b116",
    "variant": {
      "@id": "https://reg.genome.network/allele/CA220146",
      "id": "CAR:CA220146",
      "relatedContextualAllele": [
        {
          "alleleName": [
            {
              "name": "NM_002834.5:c.188A>G"
            }
          ],
          "preferred": true
        }
      ],
      "relatedIdentifier": [
        {
          "label": "NM_002834.5(PTPN11):c.188A>G (p.Tyr63Cys)"
        }
      ],
      "type": "CAR"
    }
  },
  "metadata": {
    "rendered": {
      "by": "https://erepo.genome.network/evrepo/api/summary/srvc",
      "when": "2026-10-15T17:46:51.610Z"
    }
  },
  "status": {
    "code": 200,
    "name": "OK"
  }
}