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      ],
      "id": "CG-PCER-VARINT:CA10583401/MONDO:0100488/007",
      "metadata": {
        "created": "2024-09-28T02:39:02.638Z",
        "note": "DISCLAIMER: While the data/content in this document is approved by ClinGen expert panel(s), the SEPIO schema presented here is an initial prototype and has not been reviewed nor finalized by the ClinGen Data Exchange Modeling Team. We expect it to differ significantly from the final schema.",
        "producedAtUTC": "Sat, 28 Sep 2024 02:39:02 -0000",
        "schemaLabel": "Evidence Repository.Beta-1 (Unofficial)",
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      },
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              {
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            ],
            "preferred": true
          }
        ],
        "relatedIdentifier": [
          {
            "label": "NM_004360.4(CDH1):c.79C>T (p.Pro27Ser)"
          }
        ],
        "type": "CAR"
      }
    },
    {
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        "type": "VariantPathogenicityInterpretationGuideline",
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      },
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        "@id": "https://api.monarchinitiative.org/api/bioentity/phenotype/MONDO:0100488",
        "id": "MONDO:0100488",
        "label": "CDH1-related diffuse gastric and lobular breast cancer",
        "type": "GeneticCondition"
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              ],
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                "@id": "SEPIO:0000224",
                "label": "Not Met"
              },
              "type": "CriterionAssessment"
            }
          ],
          "evidenceStrength": {
            "@id": "https://obofoundry.org/sepio"
          },
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                }
              ],
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                },
                "id": "0052",
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              ],
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                          "type": "Contribution"
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          ],
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          },
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      ],
      "id": "CG-PCER-VARINT:CA10583401/MONDO:0100488/007",
      "metadata": {
        "created": "2024-09-28T02:38:04.155Z",
        "note": "DISCLAIMER: While the data/content in this document is approved by ClinGen expert panel(s), the SEPIO schema presented here is an initial prototype and has not been reviewed nor finalized by the ClinGen Data Exchange Modeling Team. We expect it to differ significantly from the final schema.",
        "producedAtUTC": "Sat, 28 Sep 2024 02:38:03 -0000",
        "schemaLabel": "Evidence Repository.Beta-1 (Unofficial)",
        "version": "2.0.0"
      },
      "statementOutcome": {
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        "id": "LN:LA26333-7",
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      },
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      "variant": {
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        "relatedContextualAllele": [
          {
            "alleleName": [
              {
                "name": "NM_004360.4:c.79C>T"
              }
            ],
            "preferred": true
          }
        ],
        "relatedIdentifier": [
          {
            "label": "NM_004360.4(CDH1):c.79C>T (p.Pro27Ser)"
          }
        ],
        "type": "CAR"
      }
    },
    {
      "@context": "https://erepo.genome.network/evrepo/api/context",
      "@id": "https://cgerepoapi/evrepo/api/summary/classification/9a9082a0-343e-4b16-a256-c64b923d37b2/doc/sepio/version/1.0.0",
      "assertionMethod": {
        "type": "VariantPathogenicityInterpretationGuideline"
      },
      "condition": {
        "@id": "https://api.monarchinitiative.org/api/bioentity/phenotype/MONDO:0007648",
        "id": "MONDO:0007648",
        "label": "hereditary diffuse gastric cancer",
        "type": "GeneticCondition"
      },
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                    "label": "curator role",
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              ],
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                      ],
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                            "id": "SEPIO:0000516",
                            "label": "curator role",
                            "type": "ContributoryRole"
                          },
                          "type": "Contribution"
                        }
                      ],
                      "id": "CA10583401/MONDO:0007648/007/ci/CA10583401/MONDO:0007648/007.002",
                      "type": "InfFromBkgrndSciKnow"
                    }
                  ],
                  "id": "CG-PCER-VARINT:CA10583401/MONDO:0007648/007/0/1828/1830",
                  "type": "EvidenceLine"
                }
              ],
              "id": "CG-PCER-VARINT:CA10583401/MONDO:0007648/007/1/1829",
              "statementOutcome": {
                "@id": "SEPIO:0000224",
                "label": "Not Met"
              },
              "type": "CriterionAssessment"
            }
          ],
          "evidenceStrength": {
            "@id": "https://obofoundry.org/sepio"
          },
          "id": "CG-PCER-VARINT:CA10583401/MONDO:0007648/007/0/1828",
          "type": "EvidenceLine"
        },
        {
          "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA10583401/MONDO:0007648/007/el/0/1735",
          "evidenceItem": [
            {
              "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA10583401/MONDO:0007648/007/ei/1/1736",
              "contribution": [
                {
                  "agent": {
                    "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50014_EP154895050032235",
                    "id": "CG-PCER-AGENT:CG_50014_EP154895050032235",
                    "type": "Agent"
                  },
                  "contributionDate": {
                    "date": "2020/6/3",
                    "description": "Date on which this evidence was provided"
                  },
                  "contributionRole": {
                    "@id": "https://obofoundry.org/sepio/0000156",
                    "id": "SEPIO:0000516",
                    "label": "curator role",
                    "type": "ContributoryRole"
                  },
                  "type": "Contribution"
                }
              ],
              "criterion": {
                "@id": "https://obofoundry.org/sepio/clingen/0053",
                "defaultStrength": {
                  "@id": "https://obofoundry.org/sepio/SEPIO:0000330",
                  "id": "SEPIO:0000330",
                  "label": "Pathogenic Strong"
                },
                "id": "0053",
                "label": "PS4",
                "type": "Criterion"
              },
              "evidenceLine": [
                {
                  "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA10583401/MONDO:0007648/007/el/0/1735/1737",
                  "evidenceItem": [
                    {
                      "@id": "CG-PCER:curatorInference/CA10583401/MONDO:0007648/007/ci/CA10583401/MONDO:0007648/007.002",
                      "contribution": [
                        {
                          "agent": {
                            "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50014_EP154895050032235",
                            "id": "CG-PCER-AGENT:CG_50014_EP154895050032235",
                            "type": "Agent"
                          },
                          "contributionDate": {
                            "date": "2020/6/3",
                            "description": "Date on which this evidence was provided"
                          },
                          "contributionRole": {
                            "@id": "https://obofoundry.org/sepio/0000156",
                            "id": "SEPIO:0000516",
                            "label": "curator role",
                            "type": "ContributoryRole"
                          },
                          "type": "Contribution"
                        }
                      ],
                      "id": "CA10583401/MONDO:0007648/007/ci/CA10583401/MONDO:0007648/007.002",
                      "type": "InfFromBkgrndSciKnow"
                    }
                  ],
                  "id": "CG-PCER-VARINT:CA10583401/MONDO:0007648/007/0/1735/1737",
                  "type": "EvidenceLine"
                }
              ],
              "id": "CG-PCER-VARINT:CA10583401/MONDO:0007648/007/1/1736",
              "statementOutcome": {
                "@id": "SEPIO:0000224",
                "label": "Not Met"
              },
              "type": "CriterionAssessment"
            }
          ],
          "evidenceStrength": {
            "@id": "https://obofoundry.org/sepio"
          },
          "id": "CG-PCER-VARINT:CA10583401/MONDO:0007648/007/0/1735",
          "type": "EvidenceLine"
        }
      ],
      "id": "CG-PCER-VARINT:CA10583401/MONDO:0007648/007",
      "metadata": {
        "created": "2024-09-27T21:00:01.492Z",
        "note": "DISCLAIMER: While the data/content in this document is approved by ClinGen expert panel(s), the SEPIO schema presented here is an initial prototype and has not been reviewed nor finalized by the ClinGen Data Exchange Modeling Team. We expect it to differ significantly from the final schema.",
        "producedAtUTC": "Fri, 27 Sep 2024 21:00:01 -0000",
        "schemaLabel": "Evidence Repository.Beta-1 (Unofficial)",
        "version": "1.0.0"
      },
      "statementOutcome": {
        "@id": "https://loinc.org/LA26333-7",
        "id": "LN:LA26333-7",
        "label": "Uncertain Significance"
      },
      "type": "VariantPathogenicityInterpretation",
      "uuid": "9a9082a0-343e-4b16-a256-c64b923d37b2",
      "variant": {
        "@id": "https://reg.genome.network/allele/CA10583401",
        "id": "CAR:CA10583401",
        "relatedContextualAllele": [
          {
            "alleleName": [
              {
                "name": "NM_004360.4:c.79C>T"
              }
            ],
            "preferred": true
          }
        ],
        "relatedIdentifier": [
          {
            "label": "NM_004360.4(CDH1):c.79C>T (p.Pro27Ser)"
          }
        ],
        "type": "CAR"
      }
    }
  ],
  "metadata": {
    "rendered": {
      "by": "https://erepo.genome.network/evrepo/api/summary/srvc",
      "when": "2026-10-13T22:19:38.846Z"
    }
  },
  "status": {
    "code": 200,
    "name": "OK"
  }
}