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                "evidenceItem": [
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                    "@id": "CG-PCER:curatorInference/CA226605/MONDO:0010725/126/ci/CA226605/MONDO:0010725/126.002",
                    "contribution": [
                      {
                        "agent": {
                          "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50086_EP174775864491222",
                          "id": "CG-PCER-AGENT:CG_50086_EP174775864491222",
                          "type": "Agent"
                        },
                        "comments": "This variant is a missense substitution affecting a critical amino acid residue involved in disulfide bridge formation as defined by the ClinGen X-linked IRD VCEP (PMID: 26812435, PM1_Strong).",
                        "contributionDate": {
                          "date": "2025/10/3",
                          "description": "Date on which this evidence was provided"
                        },
                        "contributionRole": {
                          "@id": "https://obofoundry.org/sepio/0000156",
                          "id": "SEPIO:0000516",
                          "label": "curator role",
                          "type": "ContributoryRole"
                        },
                        "type": "Contribution"
                      }
                    ],
                    "id": "CA226605/MONDO:0010725/126/ci/CA226605/MONDO:0010725/126.002",
                    "type": "InfFromBkgrndSciKnow"
                  }
                ],
                "id": "CG-PCER-VARINT:CA226605/MONDO:0010725/126/0/1585/1587",
                "type": "EvidenceLine"
              }
            ],
            "id": "CG-PCER-VARINT:CA226605/MONDO:0010725/126/1/1586",
            "statementOutcome": {
              "@id": "SEPIO:0000224",
              "label": "Met"
            },
            "type": "CriterionAssessment"
          }
        ],
        "evidenceStrength": {
          "@id": "https://obofoundry.org/sepio"
        },
        "id": "CG-PCER-VARINT:CA226605/MONDO:0010725/126/0/1585",
        "type": "EvidenceLine"
      }
    ],
    "id": "CG-PCER-VARINT:CA226605/MONDO:0010725/126",
    "metadata": {
      "created": "2025-10-03T21:58:38.588Z",
      "note": "DISCLAIMER: While the data/content in this document is approved by ClinGen expert panel(s), the SEPIO schema presented here is an initial prototype and has not been reviewed nor finalized by the ClinGen Data Exchange Modeling Team. We expect it to differ significantly from the final schema.",
      "producedAtUTC": "Fri, 03 Oct 2025 21:58:38 -0000",
      "schemaLabel": "Evidence Repository.Beta-1 (Unofficial)",
      "version": "1.0.0"
    },
    "statementOutcome": {
      "@id": "https://loinc.org/LA6668-3",
      "id": "LN:LA6668-3",
      "label": "Pathogenic"
    },
    "type": "VariantPathogenicityInterpretation",
    "uuid": "bd5f6e2f-7f82-4dff-bb6c-660e1895fbc4",
    "variant": {
      "@id": "https://reg.genome.network/allele/CA226605",
      "id": "CAR:CA226605",
      "relatedContextualAllele": [
        {
          "alleleName": [
            {
              "name": "NM_000330.4:c.175T>A"
            }
          ],
          "preferred": true
        }
      ],
      "relatedIdentifier": [
        {
          "label": "NM_000330.4(RS1):c.175T>A (p.Cys59Ser)"
        }
      ],
      "type": "CAR"
    }
  },
  "metadata": {
    "rendered": {
      "by": "https://erepo.genome.network/evrepo/api/summary/srvc",
      "when": "2026-10-27T16:11:13.868Z"
    }
  },
  "status": {
    "code": 200,
    "name": "OK"
  }
}