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        "type": "EvidenceLine"
      },
      {
        "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA390865395/MONDO:0017288/024/el/0/1765",
        "evidenceItem": [
          {
            "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA390865395/MONDO:0017288/024/ei/1/1766",
            "contribution": [
              {
                "agent": {
                  "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50050_EP165729564243098",
                  "id": "CG-PCER-AGENT:CG_50050_EP165729564243098",
                  "type": "Agent"
                },
                "contributionDate": {
                  "date": "2022/7/8",
                  "description": "Date on which this evidence was provided"
                },
                "contributionRole": {
                  "@id": "https://obofoundry.org/sepio/0000156",
                  "id": "SEPIO:0000516",
                  "label": "curator role",
                  "type": "ContributoryRole"
                },
                "type": "Contribution"
              }
            ],
            "criterion": {
              "@id": "https://obofoundry.org/sepio/clingen/0050",
              "defaultStrength": {
                "@id": "https://obofoundry.org/sepio/SEPIO:0000330",
                "id": "SEPIO:0000330",
                "label": "Pathogenic Strong"
              },
              "id": "0050",
              "label": "PS1",
              "type": "Criterion"
            },
            "evidenceLine": [
              {
                "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA390865395/MONDO:0017288/024/el/0/1765/1767",
                "evidenceItem": [
                  {
                    "@id": "CG-PCER:curatorInference/CA390865395/MONDO:0017288/024/ci/CA390865395/MONDO:0017288/024.002",
                    "contribution": [
                      {
                        "agent": {
                          "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50050_EP165729564243098",
                          "id": "CG-PCER-AGENT:CG_50050_EP165729564243098",
                          "type": "Agent"
                        },
                        "contributionDate": {
                          "date": "2022/7/8",
                          "description": "Date on which this evidence was provided"
                        },
                        "contributionRole": {
                          "@id": "https://obofoundry.org/sepio/0000156",
                          "id": "SEPIO:0000516",
                          "label": "curator role",
                          "type": "ContributoryRole"
                        },
                        "type": "Contribution"
                      }
                    ],
                    "id": "CA390865395/MONDO:0017288/024/ci/CA390865395/MONDO:0017288/024.002",
                    "type": "InfFromBkgrndSciKnow"
                  }
                ],
                "id": "CG-PCER-VARINT:CA390865395/MONDO:0017288/024/0/1765/1767",
                "type": "EvidenceLine"
              }
            ],
            "id": "CG-PCER-VARINT:CA390865395/MONDO:0017288/024/1/1766",
            "statementOutcome": {
              "@id": "SEPIO:0000224",
              "label": "Not Met"
            },
            "type": "CriterionAssessment"
          }
        ],
        "evidenceStrength": {
          "@id": "https://obofoundry.org/sepio"
        },
        "id": "CG-PCER-VARINT:CA390865395/MONDO:0017288/024/0/1765",
        "type": "EvidenceLine"
      },
      {
        "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA390865395/MONDO:0017288/024/el/0/1699",
        "evidenceItem": [
          {
            "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA390865395/MONDO:0017288/024/ei/1/1700",
            "contribution": [
              {
                "agent": {
                  "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50050_EP165729564243098",
                  "id": "CG-PCER-AGENT:CG_50050_EP165729564243098",
                  "type": "Agent"
                },
                "contributionDate": {
                  "date": "2022/7/8",
                  "description": "Date on which this evidence was provided"
                },
                "contributionRole": {
                  "@id": "https://obofoundry.org/sepio/0000156",
                  "id": "SEPIO:0000516",
                  "label": "curator role",
                  "type": "ContributoryRole"
                },
                "type": "Contribution"
              }
            ],
            "criterion": {
              "@id": "https://obofoundry.org/sepio/clingen/0057",
              "defaultStrength": {
                "@id": "https://obofoundry.org/sepio/SEPIO:0000216",
                "id": "SEPIO:0000216",
                "label": "Pathogenic Moderate"
              },
              "id": "0057",
              "label": "PS4",
              "type": "Criterion"
            },
            "evidenceLine": [
              {
                "@id": "https://erepo.genome.network/evrepo/api/interpretation/CA390865395/MONDO:0017288/024/el/0/1699/1701",
                "evidenceItem": [
                  {
                    "@id": "CG-PCER:curatorInference/CA390865395/MONDO:0017288/024/ci/CA390865395/MONDO:0017288/024.002",
                    "contribution": [
                      {
                        "agent": {
                          "@id": "https://erepo.genome.network/evrepo/api//agent/CG_50050_EP165729564243098",
                          "id": "CG-PCER-AGENT:CG_50050_EP165729564243098",
                          "type": "Agent"
                        },
                        "comments": "2 pts: 2 unrelated probands each with PPB and other DICER1-related phenotypes (PMIDs: 26925222, 26475046)",
                        "contributionDate": {
                          "date": "2022/7/8",
                          "description": "Date on which this evidence was provided"
                        },
                        "contributionRole": {
                          "@id": "https://obofoundry.org/sepio/0000156",
                          "id": "SEPIO:0000516",
                          "label": "curator role",
                          "type": "ContributoryRole"
                        },
                        "type": "Contribution"
                      }
                    ],
                    "id": "CA390865395/MONDO:0017288/024/ci/CA390865395/MONDO:0017288/024.002",
                    "type": "InfFromBkgrndSciKnow"
                  }
                ],
                "id": "CG-PCER-VARINT:CA390865395/MONDO:0017288/024/0/1699/1701",
                "type": "EvidenceLine"
              }
            ],
            "id": "CG-PCER-VARINT:CA390865395/MONDO:0017288/024/1/1700",
            "statementOutcome": {
              "@id": "SEPIO:0000224",
              "label": "Met"
            },
            "type": "CriterionAssessment"
          }
        ],
        "evidenceStrength": {
          "@id": "https://obofoundry.org/sepio"
        },
        "id": "CG-PCER-VARINT:CA390865395/MONDO:0017288/024/0/1699",
        "type": "EvidenceLine"
      }
    ],
    "id": "CG-PCER-VARINT:CA390865395/MONDO:0017288/024",
    "metadata": {
      "created": "2024-09-28T00:07:20.884Z",
      "note": "DISCLAIMER: While the data/content in this document is approved by ClinGen expert panel(s), the SEPIO schema presented here is an initial prototype and has not been reviewed nor finalized by the ClinGen Data Exchange Modeling Team. We expect it to differ significantly from the final schema.",
      "producedAtUTC": "Sat, 28 Sep 2024 00:07:20 -0000",
      "schemaLabel": "Evidence Repository.Beta-1 (Unofficial)",
      "version": "1.0.0"
    },
    "statementOutcome": {
      "@id": "https://loinc.org/LA6668-3",
      "id": "LN:LA6668-3",
      "label": "Pathogenic"
    },
    "type": "VariantPathogenicityInterpretation",
    "uuid": "d7bb7946-aea7-4885-9715-4a46a61fd29f",
    "variant": {
      "@id": "https://reg.genome.network/allele/CA390865395",
      "id": "CAR:CA390865395",
      "relatedContextualAllele": [
        {
          "alleleName": [
            {
              "name": "NM_030621.4:c.5125G>A"
            }
          ],
          "preferred": true
        }
      ],
      "relatedIdentifier": [
        {
          "label": "NM_030621.4(DICER1):c.5125G>A (p.Asp1709Asn)"
        }
      ],
      "type": "CAR"
    }
  },
  "metadata": {
    "rendered": {
      "by": "https://erepo.genome.network/evrepo/api/summary/srvc",
      "when": "2026-05-10T15:41:23.825Z"
    }
  },
  "status": {
    "code": 200,
    "name": "OK"
  }
}