The ClinGen Evidence Repository is an FDA-recognized human genetic variant database containing expert-curated assertions regarding variants' pathogenicity and supporting evidence summaries.
[Disclaimer]
- Gene obtained from curated document aligns with the Allele Registry but not with ClinVar data
- No CSPEC computer assertion could be determined for this classification!
Variant: NM_000212.3(ITGB3):c.325del (p.Val109fs)
CA913190317
623142 (ClinVar)
Gene: ITGB3
Condition: Glanzmann thrombasthenia
Inheritance Mode: Autosomal recessive inheritance
UUID: 238fb771-9622-4285-872d-53217b890cfe
HGVS expressions
NM_000212.3:c.325del
NM_000212.3(ITGB3):c.325del (p.Val109fs)
NC_000017.11:g.47283513del
CM000679.2:g.47283513del
NC_000017.10:g.45360879del
CM000679.1:g.45360879del
NC_000017.9:g.42715878del
NG_008332.2:g.34672del
ENST00000696963.1:c.325del
ENST00000559488.7:c.325del
ENST00000559488.5:c.325del
ENST00000560629.1:c.290del
ENST00000571680.1:c.325del
NM_000212.2:c.325del
Evidence submitted by expert panel
Approved on: 2024-05-02
Published on: 2024-05-03
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